IDF2022-0737 Electromagnetic-based Implantable Sensor for Continuous Glucose Monitoring System

Continuous glucose monitoring systems (CGMS) are becoming increasingly popular in diabetes management and helps understanding physiological responses towards nutrition intake of individual. Dietary plan insulin based on CGMS data to control prevent hyper/hypo glycemic risks. Commercial the market is useful for few days months. However, electromagnetic sensor can significantly extend life CGMS. The properties do not degrade over time. Herein, development a durable, sensitive minimally invasive implant type electromagnetic-based presented. proposed utilizes oscillating nearfield detect minute permittivity changes interstitial fluid due blood level (BGL) [1]. sensor, electronic circuit board with antenna were inserted into cylindrical bioglass package 3.05 mm diameter, was sealed at both ends. NFC used powering up electronics retrieve data. also integrated temperature measure body temperature. performance evaluated healthy female beagle (4.2 kg, 10 weeks). set free after implantation move around inside animal care facility. Figure 1 shows estimated BGL from compared commercial meter (Accu-Chek). Kalman filter one-tap filtering applied remove motion induced noise dependent fluctuations. Initial 20-minute 2-point calibration sensor. High linear correlation measured observed during vivo experiment. Present work offers new perspective long term CGM system using evaluation close agreement changes.